Pathophysiological (who rounds with me knowns is one of my fav words) processes triggered by the whole-body ischemia-reperfusion response that occurs during cardiac arrest and subsequent restoration of systemic circulation.

Why it matters ? Hypoxic Ischemic Encephalopathy ( HIE) is the overall endpoint result of the post- cardiac arrest syndrome .This topic is particularly relevant to neurointsvisits because 1) they can influence it by managing  the post-cardiorespiratory arrest syndrome 2) they lead neuroprognostication.