The Neurological Pupillary Index (NPI)
npi - the machines are winning
Neurological Pupillary Index (NPi) can be used in the clinical setting to determine subtle changes in the reactivity of pupils and is correlated with ICP in a number of studies. Here's what we know and how it can be used condensed into a clinical practice guideline courtesy of the University of Cincinnati NeuroICU. There are references at that end of the protocol for further reading.